丹尼斯Giuvelis, B.S.
行为核心管理者
位置
Currently, I am the manager of the Behavior Core in the Center for 疼痛 研究. I began working in a research laboratory at UNE during the summer of 2006 as a work study student. Quickly I learned several pharmacology and behavioral neuroscience techniques and was able to start my own projects with senior members in the lab. 从全球网络赌博平台毕业后, 我管理过一个实验室, took a technical sales position that allowed me to travel worldwide and returned to UNE to manage the behavior core. Working in this role allows me to aid in designing and conducting experiments as well as training research staff and undergraduates. When I am not in the core, I am an avid runner, roller skater and dog mom.
凭证
教育
专业知识
动物行为
动物的处理
畜牧业
动物学习与行为
数据分析
阿片类药物药理学
研究设计
研究
选定的出版物
佩恩E, 哈林顿K, 理查德·P, Brackin R, 戴维斯R, 时装年代, Liff J, 斯慕斯F, Mutina E, 费舍尔一个, Giuvelis D, Sannajust S, Rostama B, King T, Mattei LM, Lee JJ, Friedman ES, Bittinger K, May M, Stevenson GW. Effects of Vancomycin on Persistent 疼痛-Stimulated and 疼痛-Depressed Behaviors in Female Fischer Rats With or Without Voluntary Access to Running Wheels. J疼痛. 2021年5月21日:S1526-5900(21)00234-0. doi: 10.1016/j.j疼痛.2021.05.003.
Beckley JT, Pajouhesh H, Luu G, Klas S, Delwig A, Monteleone D, Zhou X, Giuvelis D, Meng ID, Yeomans DC, Hunter JC, Mulcahy JV. Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of 疼痛. 疼痛. 2011年4月1日;32 (4):1250-1261. doi: 10.1097/j.疼痛.0000000000002112.
Nguyen LD, Nolte LG, Tan WJT， Giuvelis D, Santos-Sacchi J, Bilsky E, Ehrlich BE. Comprehensive somatosensory and neurological phenotyping of NCS1 knockout mice. Sci代表. 2021年1月27日;11(1):2372. doi: 10.1038/s41598-021-81650-5.
史蒂文森吉瓦, Giuvelis D, Cormier J, 锥K, 阿瑟顿P, Krivitsky R, 华纳E, 圣罗兰B, 南美洲J, Bidlack JM, 萨博L, 情节R比尔斯基EJ. Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, 炎症性和神经性疼痛, 呼吸, 自我用药. 精神药理学(Berl). 2020年4月,237 (4):1195 - 1208. doi: 10.1007/s00213-019-05449-z. 2020年1月7日.
黄齐的PN, Giuvelis D, Christensen S, Tucker KL, McIntosh JM. RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic 疼痛 in Rats. 3月的药物. 2019年12月21日;18(1):12. doi: 10.3390/md18010012.
华纳E, Krivitsky R, 锥K, 阿瑟顿P, Pitre T, Lanpher J, Giuvelis D, Bergquist I, King T比尔斯基EJ, Stevenson GW. Evaluation of a postoperative 疼痛-like state on motiviated behavior in rats: Effects of plantar incision on proressive-ratio food-maintained responding. 药物发展组. 2015年12月,76 (8):432 - 41.
Lefever M, Li Y, Anglin B, Muthu D， Giuvelis D, Lowery JJ, Knapp BI，刘建军，刘建军，刘建军. Structural requirements for CNS active opioid glycopeptides. 医学化学. 2015年8月13日;58(15):5728-41.
史蒂文森吉瓦, Luginbuhl A, Dunbar C, LaVigne J, 南美洲J, 阿瑟顿P, Bell B, 锥K, Giuvelis D李建军，李建军，李建军，等. The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats and induces in vitro markers of tolerance and dependence. 药物与生物化学行为. 2015年5月,132:49-55.
Li Y, St Louis L, Knapp BI, Muthu D, Anglin B, Giuvelis D，刘建军，刘建军，刘建军. Can amphipathic helices influence the CNS antinocicpetive activity of glycopeptides related to B-endorphin? 医学化学. 2014 Mar27; 57 (6): 2237 - 46.
Largent-Milnes TM, Brookshire SW, Skinner DP Jr, Hanlon KE, Giuvelis D,Yamamoto T, Davis P, Campos CR, Nair P, Deekonda S比尔斯基EJ, Porreca F, Hruby VJ, Vanderah TW. Building a Better Analgesic: Multifunctional Compounds that Address Injury-Induced Pathology to Enhance Analgesic Efficacy while Eliminating Unwanted Side Effects. [J]药物与实验. 347年10月2013;(1)∶7 - 19页.
Ananthan S, Saini SK, Dersch厘米, Xu H, McGlinchey N, Giuvelis D，王志强，王志强. 14-Alkoxy- and 14-acyloxypyridomorphinans: _ agonist/_ antagonist opioid analgesics with diminished tolerance and dependence side effects. 医学化学. 2012年10月11日;55(19):8350-63.
Lowery JJ, Raymond TJ， Giuvelis D，刘建军，刘建军，刘建军. In vivo characterization of MMP-2200, a mixed _/_ opioid agonist, in mice. [J]药物与实验. 2011年3月,336 (3):767 - 78.
Bilsky EJ, Giuvelis D, Osborn MD, Dersch厘米, Xu H, Rothman RB. In vitro and in vivo assessment of mu opioid receptor constitutive activity. 方法Enzymol. 2010;484:413-43.
Osborn MD, Lowery JJ, Skorput AG， Giuvelis D比尔斯基EJ. In vivo characterization of the opioid antagonist nalmefene in mice. 生命科学. 2010年4月10日;86(15-16):624-30.
Sally EJ, Xu H, Dersch厘米, Hsin LW, Chang LT, Prisinzano TE, Simpson DS, Giuvelis D, 大米KC, 雅各布森AE, 程K，王志强，王志强. Identification of a novel "almost neutral" micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. 突触. 2010年4月,64 (4):280 - 8.
heebel AC, Lee YS, Bilsky E， Giuvelis D, 德尚小, 帕里什达, 香医学博士, 也许埃尔, 哈里斯LS, 鸡笼一, Dersch厘米, Partilla JS, Rothman RB, 程K, 雅各布森AE, 大米KC. Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series. 医学化学. 2007年8月9日;50(16):3765-76.